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The biological subfamily Bovinae includes a diverse group of many genera of medium to large-sized ungulates, including cattle, bison, African buffalo, the water buffalo, the yak, and the four-horned antelope and spiral-horned antelopes. The evolutionary relationship between the members of the group is obscure, and their classification into loose tribes rather than formal subgroups reflects this uncertainty. General characteristics include cloven hoofs and usually at least one of the sexes of a species having true horns. One of the largest extant bovines is the gaur.

They date back to the Early Neogene (Early Miocene).

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